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'What is the best opening setup for this mix of pieces?'
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Are you wanting every permutation for this mix of pieces or can you define
a piece set by relative numbers?  [The latter, I hope.]

Yes, I could easily create something of similar design to the 'select CRC
analysis tool' adapted to this class of games.  It would only yield one to
a few of the most stable positions available.  It would NOT yield the most
playable positions consistent with your preferences, though, unless you
just happened to like what was also one of the most stable positions. 
Most likely, this would not be what you regard as the 'best opening
setup'.